Clinical, Surgical and Histopathologic Outcomes of Filipino Patients with Micropapillary Thyroid Carcinoma in a Tertiary University Hospital in the Philippines

Authors

  • Ruby Jane Guerrero Section of Endocrinology, Diabetes and Metabolism, University of Santo Tomas Hospital, Manila, Philippines
  • Chandy Lou Malong Section of Endocrinology, Diabetes and Metabolism, University of Santo Tomas Hospital, Manila, Philippines
  • Jean Abigaile Caringal Section of Endocrinology, Diabetes and Metabolism, University of Santo Tomas Hospital, Manila, Philippines
  • Cherry Sio Department of Surgery, University of Santo Tomas Hospital, Manila, Philippines
  • Vanessa Grace De Villa Department of Pathology, University of Santo Tomas Hospital, Manila, Philippines
  • Sjoberg Kho Section of Endocrinology, Diabetes and Metabolism, University of Santo Tomas Hospital, Manila, Philippines

Abstract

Objective.  Micropapillary thyroid carcinoma (micro-PTC) has a good prognosis but a number of cases will present with aggressive behavior. This study aims to determine the clinical outcomes with surgical management and histopathologic characteristics of Filipino patients with micro-PTC at University of Santo Tomas Hospital.

 

Methodology.  139 patients were diagnosed with micro-PTC from the year 2004-2011. Seventy five patients had complete data and were included in this retrospective study. Chi square test with Yates correction, T-test for tumor diameter, statistical means and percentages were used in data analysis.

 

Results. A total of 1,689 thyroid surgeries were  done between 2004 and 2011. There were 1,054 patients (62.4%) diagnosed with benign thyroid tumor(s) and 635 patients (37.6%) with well-differentiated thyroid carcinoma. Of these, 139 (22%) patients have micro-PTC. The prevalence rate of micro-PTC was 22%, with a female predominance (86.6%). The patients’ ages ranged from 24-80 years old with a mean age of 47 years. Comparison of groups showed that having either incidental or non-incidental micro-PTC is independent of the clinical variables of the patient. Two (2.6%) patients initially presented with cranial and supraclavicular metastasis. This study had a low recurrence rate (5.3%) and a mortality rate of 1.3%.

 

Conclusion. Male gender is the only significant variable for lymph node and distant metastasis.  The patient’s age, family history of cancer, number of foci, size and histological type of tumor have no prognostic value.

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Published

2014-05-31

How to Cite

Guerrero, R. J., Lou Malong, C., Caringal, J. A., Sio, C., De Villa, V. G., & Kho, S. (2014). Clinical, Surgical and Histopathologic Outcomes of Filipino Patients with Micropapillary Thyroid Carcinoma in a Tertiary University Hospital in the Philippines. Journal of the ASEAN Federation of Endocrine Societies, 29(1), 72. Retrieved from https://www.asean-endocrinejournal.org/index.php/JAFES/article/view/119

Issue

Vol. 29 No. 1 (2014): May Issue

Section

Original Articles

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