Prevalence of Metabolic Syndrome in Overweight and Obese Filipino Adolescents Based on the IDF Definition

Authors

  • Sioksoan Chan Cua Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines, Taft Avenue, Manila 1000 Telephone number: +632 5240892, +632 7277655 Fax number: +632 7277655

Abstract

Objective. This study determined the prevalence of metabolic syndrome (MetS) in overweight and obese Filipino adolescents.

 

Methodology. A total of 350 overweight and obese Filipino adolescents (aged 10 to 18 years, 206 males and 144 females) referred to pediatric endocrine clinics in Metro Manila were included. Weight, height, waist and blood pressure were measured and fasting lipid profiles, blood glucose and insulin were determined. MetS is defined as presence of three out of five clinical features: central obesity, hyperglycemia, hypertriglyceridemia, low HDL-C level and hypertension. The prevalence of MetS was determined based on the International Diabetes Federation (IDF) definition.

 

Results. The overall prevalence of MetS in overweight and obese adolescents was 19%. Among participants, 98% had abdominal adiposity, 25% hypertension, 24% hypertriglyceridemia, 17% low HDL and 12% hyperglycemia; 67% had hyperinsulinemia (>15 uU/ml) and 70% had insulin resistance based on HOMA-IR (≥3).   Among those with MetS, 14% had 3 components and 5% had 4 components; the prevalence of hyperinsulinemia and insulin resistance rose to 79% and 90%, respectively, with high mean levels of serum insulin (31.3 μU/ml) and HOMA-IR (7.7).

 

Conclusion. Overweight and obese adolescents are at risk to develop MetS. The prevalence of hyperinsulinemia and insulin resistance is high.

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References

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Published

2014-05-22

How to Cite

Cua, S. C. (2014). Prevalence of Metabolic Syndrome in Overweight and Obese Filipino Adolescents Based on the IDF Definition. Journal of the ASEAN Federation of Endocrine Societies, 27(1), 82. Retrieved from https://www.asean-endocrinejournal.org/index.php/JAFES/article/view/18

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Original Articles