TY - JOUR AU - Sanjiwani, Made Indira Dianti AU - Aryadi, I Putu Hendri AU - Semadi, I Made Siswadi PY - 2022/04/21 Y2 - 2024/03/29 TI - Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus JF - Journal of the ASEAN Federation of Endocrine Societies JA - J ASEAN Fed Endocr Soc VL - 37 IS - 1 SE - *Review Articles DO - 10.15605/jafes.037.01.13 UR - https://asean-endocrinejournal.org/index.php/JAFES/article/view/1127 SP - 69-74 AB - <p><em>Akkermansia muciniphila</em> is a promising gut microbiota for the treatment of type 2 diabetes mellitus (T2DM). <em>A. muciniphila</em> stimulates intestinal wall integrity, is an anti-inflammatory agent, and reduces endoplasmic reticulum stress, lipogenesis and gluconeogenesis. These properties make <em>A. muciniphila</em> a&nbsp; potential treatment option for T2DM by reducing insulin resistance and increasing insulin sensitivity and glucose tolerance in different tissues. This article explores the possible role of <em>A. muciniphila </em>in T2DM management, along with the various methods known to modulate <em>A. muciniphila</em>.</p> ER -