TY - JOUR AU - Gan, Florence Rochelle AU - Gomez, Maria Honolina AU - Tapispisan, Julie Ann PY - 2022/05/12 Y2 - 2024/03/28 TI - Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino using Definitive Chemotherapy followed by Radiotherapy: A Case Report JF - Journal of the ASEAN Federation of Endocrine Societies JA - J ASEAN Fed Endocr Soc VL - 37 IS - 1 SE - Case Reports DO - 10.15605/jafes.037.01.12 UR - https://asean-endocrinejournal.org/index.php/JAFES/article/view/1259 SP - 97-102 AB - <p>We report a case of a 24-year-old Filipino male who complained of general weakness, polydipsia, weight loss, bitemporal headaches, loss of libido and behavioral changes. Endocrine work-up revealed neurogenic diabetes insipidus and panhypopituitarism. &nbsp;Brain MRI showed multiple intracranial tumors in the left frontal lobe, pineal and suprasellar region with moderate non-communicating hydrocephalus. Intracranial mass biopsy with ventriculo-peritoneal shunting was done. Histopathology of the mass and CSF revealed a germinoma. He underwent chemoradiotherapy while on maintenance hormone replacement.</p> ER -