EFFECT OF 32 GRAM RESISTANT STARCH SNACK ON GLUCAGON LEVEL OF OBESE PATIENTS WITH DM TYPE 2

Authors

  • Nur Anna Chalimah Sadyah Rumah Sakit Islam Sultan Agung Medical Faculty, Sultan Agung Islamic University, Semarang, Indonesia
  • Hemi Sinorita RSUP Dr. Sardjito Medical Faculty, Gadjah Mada University, Yogyakarta, Indonesia
  • M. Robikhul Ikhsan RSUP Dr. Sardjito Medical Faculty, Gadjah Mada University, Yogyakarta, Indonesia

Keywords:

type 2 diabetes, glucagon, resistant starch

Abstract

INTRODUCTION Glucagon plays a role in the pathophysiology of hyperglycemia in patients with type 2 Diabetes (DM). The characteristic of nutritional therapy for patients with type 2DM is using the resistant starch. This study was aimed to determine the influence of administration of 32 g snack made from resistant starch on glucagon level.

METHODOLOGY
This was a angle-arm before and after clinical trial design conducted among 21 obese patients with type 2DM attending endocrine clinic at RSUD Sarjito. The fasting glucagon levels were evaluated before and one hour after the administration of resistant starch.

RESULTS
 Mean fasting glucose before and after snack with resistant starch were 203.18±132 and 201.64 pg/mL±33.84 pg/mL respectively. There was no significant difference in the fasting glucagon (p=0.170). Thirty-eight patients had a decrease in fasting glucose (11.92 pg/mL and 9.5 pg/mL respectively). The administration of resistant starch was very weakly correlated with the decrease in fasting glucagon (r=0.174)

CONCLUSION
 There was no change in plasma glucagon level with administration of 32 gram snack made from resistant starch.

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Published

2022-05-29

How to Cite

Sadyah, N. A. C., Sinorita, H., & Ikhsan, M. R. (2022). EFFECT OF 32 GRAM RESISTANT STARCH SNACK ON GLUCAGON LEVEL OF OBESE PATIENTS WITH DM TYPE 2. Journal of the ASEAN Federation of Endocrine Societies, 34(2), 25. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/1939

Issue

Vol. 34 No. 2 (2019): AFES Book of Abstracts (Supplement)

Section

Abstracts of Original Articles | Prediabetes, Diabetes Mellitus, Hypoglycemia

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