Parathyroidectomy for Refractory Secondary Hyperparathyroidism with Severe Bone Disease


  • Teodora Amor N. Evora Section of Endocrinology and Metabolism, St. Luke’s Medical Center, Quezon City, Philippines
  • Roberto C. Mirasol Section of Endocrinology and Metabolism, St. Luke’s Medical Center, Quezon City, Philippines


Advances in the medical management of secondary hyperparathyroidism due to renal failure have decreased the use of parathyroidectomy as a treatment option. However, some patients with end-stage renal disease still progress to refractory hyperparathyroidism and debilitating bone disease, for which parathyroidectomy may be warranted.  We describe a case of a 35-year-old female on chronic hemodialysis who presented with bone pains, deformities, decrease in height and recurrent pathologic fractures. She had markedly elevated parathyroid hormone (PTH), vitamin D deficiency, persistent hyperphosphatemia and hypocalcemia despite therapeutic measures. Subtotal parathyroidectomy was done with eventual improvement of biochemical abnormalities, resolution of bone pains and healing of fractures.


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How to Cite

Evora, T. A. N., & Mirasol, R. C. (2014). Parathyroidectomy for Refractory Secondary Hyperparathyroidism with Severe Bone Disease. Journal of the ASEAN Federation of Endocrine Societies, 27(1), 105. Retrieved from



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