THE EFFECTS OF DRY INTERMITTENT FASTING ON OVERWEIGHT AND OBESITY

PROTOCOL FOR A NON-RANDOMIZED CONTROLLED TRIAL

Authors

  • Shazana Rifham Abdullah Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Nur Hayati Azizul Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Ruziana Mona Wan Mohd Zin Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Nur Suffia Sulaiman Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Norhayati Mustafa Khalid Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Roshan Jahn Mohd Salim Mullahi Jahn Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Muhammad Khairul Nazri Khalil Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Nur Azlin Zainal Abidin Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Azizan Ali Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Tan You Zhuan Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia
  • Mohd Azahadi Omar Biostatistic and Data Repository Unit, National Institutes of Health, Ministry of Health Malaysia
  • Mohammad Zabri Johari Institute for Health Behavioural Research, National Institutes of Health, Ministry of Health Malaysia
  • Nur Shahida Abdul Aziz Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia
  • Azli Baharudin Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia
  • Zamtira Seman Biostatistic and Data Repository Unit, National Institutes of Health, Ministry of Health Malaysia
  • Mona Lisa Md Rasip Occupational Safety and Health Unit, National Institutes of Health, Ministry of Health Malaysia
  • Mohd Fairulnizal Md Noh Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia

Keywords:

dry intermittent fasting, overweight, obesity, protocol

Abstract

INTRODUCTION

In line with the increasing trend of overweight and obesity prevalence worldwide, stakeholders have been strengthening the efforts to promote obesity prevention programs. Although wet intermittent fasting has been proven effective in reducing weight and is widely practised nowadays, the effectiveness of two-days per week dry fasting is still unclear. The Cardiometabolic and Anthropometric Outcomes of Intermittent Fasting (CAIFA) study aimed to determine the cardiometabolic, anthropometric, dietary and quality of life changes among overweight and obese civil servants following combined intermittent fasting and healthy plate (IFHP) and healthy plate (HP) alone. This study also explored the participants’ experience with both methods.

METHODOLOGY

The CAIFA study is a mixed-method quasi-experimental study examining the effectiveness of IFHP and HP methods among overweight and obese adults. A total of 177 participants participated in this study, of which 91 were allocated in the IFHP group and 86 in the HP group. The intervention involve two phases: a supervised phase (12 weeks) and an unsupervised phase (12 weeks). The data collection was conducted during baseline visit, after the supervised phase, and at the end of the unsupervised phase. Data on socio-demographics, quality of life, physical activity and dietary intake were also obtained. Serum and whole blood were collected from each participant for analysis.

RESULTS

Most of the participants were females (n=147, 83.7%) and Malays (n=141, 79.6%). The outcomes included in this study were changes in body weight, body composition, quality of life, physical activity, dietary intake and cardiometabolic parameters such as fasting blood glucose, 2-hour postprandial blood glucose, HbA1c, fasting insulin and lipid profile.

CONCLUSION

We established a mixed-method study to assess the effectiveness of combined IFHP and HP interventions on cardiometabolic and anthropometric parameters and to explore participants’ experience throughout the study

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Published

2022-07-15

How to Cite

Abdullah, S. R., Azizul, N. H. ., Wan Mohd Zin, R. M., Sulaiman, . N. S., Khalid, N. M. ., Jahn, . R. J. M. S. M., … Md Noh, M. F. (2022). THE EFFECTS OF DRY INTERMITTENT FASTING ON OVERWEIGHT AND OBESITY: PROTOCOL FOR A NON-RANDOMIZED CONTROLLED TRIAL. Journal of the ASEAN Federation of Endocrine Societies, 37, 33. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/2335

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