USE OF EPLERENONE IN PRIMARY ALDOSTERONISM DURING PREGNANCY

A CASE SERIES

Authors

  • Denise Joy Emmanuelle Lopez
  • Lou Erika Rubion
  • Maria Patricia Deanna Maningat-Goco

Keywords:

primary aldosteronism, pregnancy, eplerenone

Abstract

CASE
We describe 2 patients with biochemically confirmed primary aldosteronism (PA) who were treated with eplerenone during pregnancy. Both patients were diagnosed with PA prior to pregnancy but were lost to follow-up since the pandemic. Patient 1 is a 32-year-old gravida 3 para 3 with a previous preterm delivery, seen at 26 weeks age of gestation and referred for elevated blood pressure of 160/110mmHg with severe hypokalemia. Patient 2 is a 40-year-old Gravida 6 Para 5 with previous preterm delivery as well. She was seen at 25 weeks age of gestation and referred for elevated blood pressure of 140/90mmHg and hypokalemia of 2.9 mmol/L. Both patients were given eplerenone 25 mg twice daily and had improvement in blood pressure and hypokalemia thereafter. Both patients had preterm births with birthweights appropriate for age, and APGAR scores of 9 after 5 minutes. This case series can support the efficacy of the short-term use of eplerenone to control hypertension and hypokalemia in PA during pregnancy

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Author Biographies

Denise Joy Emmanuelle Lopez

University of the Philippines - Philippine General Hospital

Lou Erika Rubion

University of the Philippines - Philippine General Hospital

Maria Patricia Deanna Maningat-Goco

University of the Philippines - Philippine General Hospital

References

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Published

2023-11-09

How to Cite

Lopez, D. J. E., Rubion, L. E., & Maningat-Goco , M. P. D. (2023). USE OF EPLERENONE IN PRIMARY ALDOSTERONISM DURING PREGNANCY: A CASE SERIES. Journal of the ASEAN Federation of Endocrine Societies, 38(S3), 40. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/3273

Issue

Vol. 38 No. S3 (2023): AFES Book of Abstracts (Supplement)

Section

Poster Presentation | Adrenal

License

Copyright (c) 2023 Denise Joy Emmanuelle Lopez, Lou Erika Rubion, Maria Patricia Deanna Maningat-Goco

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