ANCIENT SCHWANNOMA

A GREAT MIMICKER OF ADRENAL TUMOUR

Authors

  • Chee Koon Low
  • Zanariah Hussein
  • Yi Jiang Chua
  • Yee Ling Tan
  • Noorasmaliza Md Paiman

Keywords:

SCHWANNOMA, ADRENAL, retroperitoneal schwannoma

Abstract

INTRODUCTION/BACKGROUND
Retroperitoneal schwannoma is a benign neoplasm arising from the neural crest cells. Pre-operative diagnosis of this rare tumour is often difficult due to its enormous size at the time of presentation and the lack of distinctive imaging phenotypes. We share a case of an incidentally discovered huge right periadrenal ancient schwannoma in an elderly patient who suffered from an underlying nasopharyngeal carcinoma.

CASE
A 70-year-old male was found to have a 15-cm right suprarenal mass when he underwent CT scan for the staging of nasopharyngeal carcinoma. He had no paroxysmal symptoms or hypertension. There were no features of Cushing syndrome. Endocrine evaluation showed no evidence of functioning pheochromocytoma or adrenocortical carcinoma. The patient underwent open adrenalectomy and tumour excision uneventfully. Pathology examination revealed a large ancient schwannoma consisting of spindle cells with nuclear and cytoplasmic S-100 positivity.

CONCLUSION
The pre-operative diagnosis of retroperitoneal schwannoma remains challenging despite the advances in imaging modalities. Th definitive diagnosis relies on biopsy or

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Author Biographies

Chee Koon Low

Endocrine Unit, Department of Medicine, Hospital Putrajaya, Malaysia

Zanariah Hussein

Endocrine Unit, Department of Medicine, Hospital Putrajaya, Malaysia

Yi Jiang Chua

Endocrine Unit, Department of Medicine, Hospital Putrajaya, Malaysia

Yee Ling Tan

Endocrine and Breast Surgery Unit, Department of Surgery, Hospital Putrajaya, Malaysia

Noorasmaliza Md Paiman

Department of Pathology, Hospital Putrajaya, Malaysia

References

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Published

2024-07-17

How to Cite

Low, C. K., Hussein, Z., Chua, Y. J., Tan, Y. L., & Paiman, N. M. (2024). ANCIENT SCHWANNOMA: A GREAT MIMICKER OF ADRENAL TUMOUR. Journal of the ASEAN Federation of Endocrine Societies, 39(S1), 14–15. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/4417

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