Aldosterone-Producing Adrenocortical Carcinoma with Co-Secretion of Cortisol and Estradiol: A Case Report



adrenal cancer, adrenocortical carcinoma, hyperaldosteronism, hypertension


Aldosterone-producing adrenocortical carcinoma comprises less than 7% of all functioning adrenocortical carcinomas. We report a rare case of adrenocortical carcinoma with a clinical picture of primary aldosteronism and subclinical Cushing’s syndrome and feminization. Complete surgical resection normalized blood pressures and aldosterone, cortisol and estradiol levels. Long-term monitoring is recommended with imaging and hormonal evaluation used as tumor markers for recurrence.


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Author Biographies

Karen Lazaro, The Medical City

Fellow-in-training, Section of Endocrinology, Diabetes and Metabolism, The Medical City

Perie Adorable-Wagan, The Medical City

Consultant, Section of Endocrinology, Diabetes and Metabolism


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How to Cite

Lazaro, K., & Adorable-Wagan, P. (2018). Aldosterone-Producing Adrenocortical Carcinoma with Co-Secretion of Cortisol and Estradiol: A Case Report. Journal of the ASEAN Federation of Endocrine Societies, 33(1), 57. Retrieved from



Case Reports