THYROID NODULES IN CHILDREN

OUTCOME AND THERAPY

Authors

  • Naily Athirah Hamidun Majid
  • Muhammad Danial Abdul Rahman
  • Nur Sabrina Rusli
  • Nurshadia Samingan
  • Annie Leong
  • Muhammad Yazid Jalaludin
  • Azriyanti Anuar Zaini

Keywords:

THYROID, NODULES, papillary

Abstract

INTRODUCTION
Thyroid nodules occur less frequently in children compared to adults. The estimated prevalence of solid thyroid nodules is approximately 1% to 1.7% of the paediatric population, with the incidence increasing with age. This study aimed to describe the prevalence and outcomes of paediatric patients with thyroid nodule.

METHODOLOGY
Children and adolescents diagnosed with thyroid nodules from 2012 to 2024 at the University Malaya Medical Centre were included in this retrospective review.

RESULT
Twelve patients were referred and diagnosed with thyroid nodule (s). Most were female (91.7%), with a mean age at diagnosis of 12.97 ± 1.97 years. Multinodular goitre was seen in 58.3%. The prevalence of thyroid nodules among paediatric patients with thyroid disease including congenital and acquired cases in our centre was 2%. Seven (58.3%) were Chinese, 4 (33.3%) Malay, and 1 (8.3%) Indian. Seven (58.3%) patients presented with goitre, while 4 (33.3%) were referred post-total thyroidectomy and 1 (8.3%) with symptoms of hyperthyroidism (tremors and palpitations). Eight (66.7%) patients were euthyroid and 3 (25%) were hypothyroid post-total thyroidectomy. Fine needle aspiration cytology was done in 10 (83.3%) patients. Four (33.3%) were confirmed malignant. Of the 4 patients with papillary thyroid cancer, 3 (75%) patients were initially diagnosed with a solitary thyroid nodule. Their mean age at presentation was 12.83 ± 1.66 years, and all underwent total thyroidectomy. One (8.3%) patient developed hypercalcaemic seizure after thyroidectomy. None developed vocal cord paralysis.

CONCLUSION
The prevalence of thyroid nodules in our centre is similar to other studies, with multinodular goitre being most diagnosed. The majority of adolescents with papillary thyroid cancer presented with solitary thyroid nodules. Total thyroidectomy in papillary thyroid cancer is safe with minimal complications.

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Author Biographies

Naily Athirah Hamidun Majid

Department of Paediatrics, University Malaya, Malaysia

Muhammad Danial Abdul Rahman

Department of Paediatrics, University Malaya, Malaysia

Nur Sabrina Rusli

Department of Paediatrics, University Malaya, Malaysia

Nurshadia Samingan

Department of Paediatrics, University Malaya, Malaysia

Annie Leong

Department of Paediatrics, University Malaya, Malaysia

Muhammad Yazid Jalaludin

Department of Paediatrics, University Malaya, Malaysia

Azriyanti Anuar Zaini

Department of Paediatrics, University Malaya, Malaysia

References

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Published

2024-07-17

How to Cite

Majid, N. A. H., Rahman, M. D. A., Rusli, N. S. ., Samingan, N., Leong, A., Jalaludin, M. Y., & Zaini, A. A. (2024). THYROID NODULES IN CHILDREN: OUTCOME AND THERAPY. Journal of the ASEAN Federation of Endocrine Societies, 39(S1), 127. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/4833

Issue

Section

Abstracts for Poster Presentation | Paediatric

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