Vitamin D Status and Dyslipidaemia among  Obese Individuals in Ibadan, Nigeria: A Pilot Study

Oyebola Sonuga; Zainab Shittu; Ayobola Sonuga; Kayode Adedapo; Comfort Folashade Adekanye

doi:10.15605/jafes.040.02.09

Authors

Oyebola Oluwagbemiga Sonuga University of Ibadan, Nigeria https://orcid.org/0000-0002-5951-3703
Zainab Omobolanle Shittu University College Hospital
Ayobola Sonuga Lead City University, Ibadan, Nigeria https://orcid.org/0000-0001-5461-1067
Kayode Adedapo University of Ibadan, Nigeria https://orcid.org/0000-0002-0251-5636
Comfort Folashade Adekanye University College Hospital, Ibadan, Nigeria

DOI:

https://doi.org/10.15605/jafes.040.02.09

Keywords:

obesity, dyslipidaemia, vitamin D status, atherogenic index

Abstract

Objective. Obesity is a major global health concern characterized by an accumulation of excessive body fat, dyslipidaemia and low vitamin D levels. This study aimed to assess the relationship between dyslipidaemia and vitamin D status in obese individuals and the risk of atherogenesis.

Methodology. In this cross-sectional study, 140 participants aged 18 to 65 years, were categorized into 4 equal groups of 35 each, based on their body mass index BMI. Baseline and demographic data were obtained using a semi-structured questionnaire. The serum levels of vitamin D, total cholesterol (TC), triglyceride (TG) and HDL-cholesterol (HDL-c) were measured using standard methods. Low-density lipoprotein cholesterol (LDL-c) and atherogenic index in plasma (AIP) were calculated.

Results. The vitamin D status was sufficient in all groups but its concentrations decline significantly as BMI increases. Serum TC, TG, LDL-c concentration significantly increases as BMI increases, but HDL-c concentration decreases. The AIP increases as BMI increases.

Conclusion. The study provided possible evidence to support the association between dyslipidaemia and inadequate vitamin D status in this cohort of adults with obesity in Ibadan, Nigeria.

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Author Biographies

Oyebola Oluwagbemiga Sonuga, University of Ibadan, Nigeria

Adjunct Lecturer, Chemical Pathology Department, University of Ibadan, Nigeria

Zainab Omobolanle Shittu, University College Hospital

Research Assistnt, Department of Chemical Pathology, University College Hospital, Ibadan, Nigeria

Ayobola Sonuga, Lead City University, Ibadan, Nigeria

Senior Lecturer, Department if Biochemistry, Lead City University, Ibadan, Nigeria

Kayode Adedapo, University of Ibadan, Nigeria

Professor, Department of Chemical Pathology, University of Ibadan, Nigeria

Comfort Folashade Adekanye, University College Hospital, Ibadan, Nigeria

Department of Chemical Pathology, University College Hospital, Ibadan, Nigeria

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