Falsely Elevated Serum Testosterone Levels in a Young Adult Female with Polycystic Ovarian Syndrome (PCOS) and Left Adrenal Adenoma

  • Yin Chian Kon Department of Endocrinology, Tan Tock Seng Hospital, Singapore
  • Robert Hawkins Department of Laboratory Medicine, Tan Tock Seng Hospital, Singapore


Serum testosterone immunoassay interference may cause falsely high results. We report a case of 20-year-old female with PCOS whose initial serum testosterone levels were more than 10 nM. Further imaging revealed a left adrenal adenoma. During an attempt at bilateral adrenal-ovarian venous sampling at another institution, her peripheral serum total testosterone levels on a different assay platform were surprisingly normal. Subsequently, simultaneous samples performed on three different assay platforms confirmed the presence of assay interference from the originating institution.


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How to Cite
Kon, Y. C., & Hawkins, R. (2014). Falsely Elevated Serum Testosterone Levels in a Young Adult Female with Polycystic Ovarian Syndrome (PCOS) and Left Adrenal Adenoma. Journal of the ASEAN Federation of Endocrine Societies, 28(2), 159. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/70
Case Reports