Primary Partial Empty Sella presenting with Prepubertal Hypogonadotropic Hypogonadism

A Case Report

Keywords: PES, hypogonadotropic, hypogonadism, micropenis

Abstract

Primary partial empty sella occurs when less than 50% of an enlarged or deformed sella turcica is filled with cerebrospinal fluid in the setting of unidentified etiologic pathological conditions. Prepubertal hypogonadotropic hypogonadism presenting as its main manifestation is rare since its peak incidence commonly occurs late at 30 to 40 years of age and has a sexual predilection for female. We described a case of 20-year-old male who presented with micropenis and absent secondary sex characteristics. Work up showed cranial MRI finding of partial empty sella, low testosterone, LH, FSH, Estradiol and Beta HCG levels. Sex hormone replacement may not improve fertility for this case but may help produce and maintain virilization and prevent future complications of hypogonadotropic hypogonadism.

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Author Biographies

Maria Angela Matabang, Ospital ng Makati, Makati City

Medical Resident, Department of Internal Medicine

Buena Sapang, Cardinal Santos Medical Center, San Juan City

Department of Endocrinology

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Published
2020-11-04
How to Cite
Matabang, M. A., & Sapang, B. (2020). Primary Partial Empty Sella presenting with Prepubertal Hypogonadotropic Hypogonadism: A Case Report. Journal of the ASEAN Federation of Endocrine Societies, 35(2). Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/895
Section
Case Reports