Primary Hypoparathyroidism and Non-functioning Pituitary Adenoma: An Incidental Coexistence?


  • Lit Sin Yong Department of Medicine, Hospital Tuanku Ja’afar Seremban, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia
  • Noorlita Adam Department of Medicine, Hospital Tuanku Ja’afar Seremban, Jalan Rasah, Seremban, Negeri Sembilan, Malaysia


Primary hypoparathyroidism is caused by a group of heterogeneous conditions in which hypocalcemia and hyperphosphatemia occur as a result of deficient parathyroid hormone (PTH) secretion. The most common cause is surgical excision and damage to the parathyroid gland(s). Nonetheless, autoimmune endocrine disorder of primary hypothyroidism has been well-described in polyglandular autoimmune syndromes (PAS).1 Its association with pituitary lesion may be autoimmune lymphocytic hypophysitis as the cause for pituitary disorder. In this report, we encountered a patient with primary hypoparathyroidism who had a non-functioning pituitary tumour. It was confirmed as pituitary adenoma rather than lymphocytic hypophysitis from the histopathological examination. To our knowledge, this is the first reported case of non-functioning pituitary macroadenoma and primary hypoparathyroidism.


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How to Cite

Yong, L. S., & Adam, N. (2014). Primary Hypoparathyroidism and Non-functioning Pituitary Adenoma: An Incidental Coexistence?. Journal of the ASEAN Federation of Endocrine Societies, 29(1), 86. Retrieved from



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