ASSOCIATION OF SERUM MAGNESIUM LEVELS WITH FASTING PLASMA GLUCOSE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS ON METFORMIN OR PIOGLITAZONE
Keywords:
serum magnesium level, fasting plasma, glucose, type 2 diabetes mellitusAbstract
INTRODUCTION
The aim of this study is to analyze the association between serum magnesium level and fasting plasma glucose in patients with type 2 diabetes mellitus (DM) who had taken metformin or pioglitazone.
METHODOLOGY
Serum magnesium level and fasting plasma glucose were examined from a total of 41 patients whose type 2 diabetes was controlled with metformin ≥750 mg/day for at least 3 weeks or pioglitazone ≥15 mg/day for at least 4 weeks with a body mass index (BMI) of <30 kg/m2 . Fasting plasma glucose was analyzed using Roche/Hitachi Cobas C System. Serum magnesium level was analyzed using Roche/Hitachi Cobas C311/501 System.
RESULTS
The mean value of serum magnesium levels was 2.04±0.19 mg/dL. The median of fasting plasma glucose was 131±40, 85 mg/dL. The lower level of the serum magnesium had a significant correlation with fasting plasma glucose.
CONCLUSION
There is a significant negative correlation between the serum magnesium levels and fasting plasma glucose in type 2 DM on metformin or pioglitazone.
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