SCROTAL PYOCELE ASSOCIATED WITH SODIUM-GLUCOSE CO-TRANSPORTER 2 INHIBITOR (SGLT2i)

THE NEED FOR HIGH INDEX OF SUSPICION

Authors

  • Yotsapon Thewjitcharoen Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand
  • Nampetch Lekpittaya Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand
  • Soontaree Nakasatien Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand
  • Somsong Polchart Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand
  • Suchart Chaimuangraj Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand
  • Thep Himathongkam Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand

Keywords:

SGLT2i, scrotum, pyocele, urinary tract infection

Abstract

INTRODUCTION
Recent data showed that SGLT2i is linked with Fournier gangrene. Scrotal pyocele is a rare clinical condition often commonly associated with acute epididymoorchitis. Previous evidence suggested potential risk of serious genitourinary infection in patients using SGLT2i. however, scrotal pyocele associated with SGLT2i has never been reported.

CASE
A patient with poorly-controlled type 2 DM on SGLT2i presented with acute scrotal pain.

CONCLUSION
Although rare, SGLT2i may result in serious genitourinary infection including scrotal pyocele. Clinicians must take great care when prescribing SGLT2i to elderly male patients with pre-existing hydrocele. Treatment requires broadspectrum antibiotics and emergent surgical consultation to prevent testicular damage or Fournier gangrene.

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Published

2022-06-08

How to Cite

Thewjitcharoen, Y., Lekpittaya, N., Nakasatien, S., Polchart, S., Chaimuangraj, S., & Himathongkam, T. (2022). SCROTAL PYOCELE ASSOCIATED WITH SODIUM-GLUCOSE CO-TRANSPORTER 2 INHIBITOR (SGLT2i): THE NEED FOR HIGH INDEX OF SUSPICION. Journal of the ASEAN Federation of Endocrine Societies, 34(2), 52. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/2033

Issue

Section

Abstracts of Case Reports | Prediabetes, Diabetes, Hypoglycemia

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