Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
DOI:
https://doi.org/10.15605/jafes.038.02.21Keywords:
corneal confocal microscopy, small fibre, autonomic neuropathy, hypoglycaemia, T1DMAbstract
Impaired awareness of hypoglycaemia (IAH) is present in around 25-40% of individuals with type 1 diabetes mellitus (T1DM). Herein, we present a case of an adolescent with T1DM and IAH who had worse corneal nerve parameters compared to a T1DM adolescent without IAH. Small fibre abnormalities detected by corneal confocal microscopy in an objective easy-to-perform non-invasive test might be a surrogate indicator of underlying autonomic dysfunction in T1DM and IAH.
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Copyright (c) 2023 Mainak Banerjee, Pradip Mukhopadhyay, Madhurima Basu, Sujoy Ghosh
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