Uric Acid Crystalluria following the Recovery Phase of Diabetic Ketoacidosis (DKA): A Lesser-known Complication of DKA

Yotsapon Thewjitcharoen; Nopparath Thongpoo; Worawit Kittipoom

doi:10.15605/jafes.039.01.20

Uric Acid Crystalluria following the Recovery Phase of Diabetic Ketoacidosis (DKA)

A Lesser-known Complication of DKA

Authors

Yotsapon Thewjitcharoen Theptarin Hospital https://orcid.org/0000-0002-2317-4041
Nopparath Thongpoo Theptarin Hospital https://orcid.org/0009-0009-3559-4711
Worawit Kittipoom Theptarin Hospital https://orcid.org/0000-0002-5581-2765

DOI:

https://doi.org/10.15605/jafes.039.01.20

Keywords:

Crystalluria, Uric acid, Diabetic Ketoacidosis

Abstract

The occurrence of hyperuricemia is frequently associated with diabetic ketoacidosis (DKA), however, crystalluria from the precipitation of calcium oxalate, uric acid, or urate crystals, is less known. Metabolic derangements during DKA, especially acidic urinary pH and hyperuricosuria are the main risk factors for uric acid crystals and stones. Here we report a case of uric acid crystalluria following the recovery phase of DKA.

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Author Biographies

Yotsapon Thewjitcharoen, Theptarin Hospital

Diabetes and Thyroid Center

Nopparath Thongpoo, Theptarin Hospital

Diabetes and Thyroid Center

References

Padova J, Bendersky G. Hyperuricemia in diabetic ketoacidosis. N Engl J Med. 1962;267: 530-4. https://pubmed.ncbi.nlm.nih.gov/14483098. https://doi.org/10.1056/NEJM196209132671102.

Agrawal S, Kremsdorf R, Uysal S, Fredette ME, Topor LS. Nephrolithiasis: A complication of pediatric diabetic ketoacidosis. Pediatr Diabetes. 2018;19(2):329-32. https://pubmed.ncbi.nlm.nih.gov/28737266. https://doi.org/10.1111/pedi.12559.

Shimazaki S, Kazukawa I, Mori K, Kihara M, Minagawa M. Acute kidney injury caused by ammonium acid urate crystals in diabetic ketoacidosis at the onset of type 1 diabetes mellitus. Endocrinol Diabetes Metab Case Rep. 2021;2021:20-0143. https://pubmed.ncbi.nlm.nih.gov/33865236. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923033. https://doi.org/10.1530/EDM-20-0143.

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Published

2024-05-05

How to Cite

Thewjitcharoen, Y., Thongpoo, N., & Kittipoom, W. (2024). Uric Acid Crystalluria following the Recovery Phase of Diabetic Ketoacidosis (DKA): A Lesser-known Complication of DKA. Journal of the ASEAN Federation of Endocrine Societies, 39(1), 129–130. https://doi.org/10.15605/jafes.039.01.20

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Issue

Vol. 39 No. 1 (2024): May Issue

Section

Images in Endocrinology

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