A Tumultuous Journey of Metastatic Pancreatic Neuroendocrine Tumor with Carcinoid Syndrome

Authors

  • Somdatta Giri Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) https://orcid.org/0000-0002-3464-7860
  • Sadishkumar Kamalanathan Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
  • Kalayarasan Raja Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
  • Nandini Pandit Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) https://orcid.org/0000-0001-9300-7444
  • Jayaprakash Sahoo Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
  • Dukhabandhu Naik Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Keywords:

pancreatic neuroendocrine tumor, metastatic, octreotide refractory, peptide receptor radionuclide therapy, norepinephrine

Abstract

A 25-year-old woman presented with metastatic pancreatic neuroendocrine tumor with carcinoid syndrome. She was  refractory to octreotide and did not respond well to chemotherapy. Although, surgical debulking remains the primary approach for managing these tumours, it entails inherent risks, including potentially exacerbating carcinoid syndrome. We strategically delivered the one Peptide Receptor Radionuclide Therapy cycle before tumor debulking, a decision that yielded a remarkable response, stabilizing her condition.

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Author Biographies

Somdatta Giri, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Sadishkumar Kamalanathan, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Kalayarasan Raja, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Department of Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Nandini Pandit, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Department of Nuclear Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Jayaprakash Sahoo, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Dukhabandhu Naik, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

Published

2025-01-24

How to Cite

Giri, S., Kamalanathan, S., Raja, K., Pandit, N., Sahoo, J., & Naik, D. (2025). A Tumultuous Journey of Metastatic Pancreatic Neuroendocrine Tumor with Carcinoid Syndrome. Journal of the ASEAN Federation of Endocrine Societies. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/3115

Issue

Forthcoming Articles

Section

Case Reports

License

Copyright (c) 2025 Somdatta Giri, Sadishkumar Kamalanathan, Kalayarasan Raja, Nandini Pandit, Jayaprakash Sahoo, Dukhabandhu Naik

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