NAVIGATING THE DIAGNOSTIC CHALLENGES OF CALCIPENIC RICKETS COMPLICATED BY HYPERCOAGULATION, HYPOKALEMIA, AND SECONDARY AMENORRHEA IN A 21-YEAR-OLD FEMALE

Authors

  • Merylla Filianty Sipayung
  • Ratna Maila Dewi Anggraini
  • Alwi Shahab
  • Yulianto Kusnadi
  • Mediarty Syahrir
  • Radiyati Umi Partan

Keywords:

rickets, vitamin D, diagnosis

Abstract

CASE
Rickets, a metabolic bone disorder primarily attributed to insufficient mineralization of the epiphyseal plate or osteoid calcification failure due to vitamin D or calcium deficiency, encompasses a spectrum of etiological factors including genetic anomalies and drug-induced manifestations. This report details a case of calcipenic rickets in a 21-year-old Indonesian female who presented with growth retardationand leg deformities since age 13. Extensive evaluation revealed hypocalcemia, hyperparathyroidism, elevated alkaline phosphatase, reduced phosphate levels, and decreased vitamin 25(OH)D concentrations. Alongside calcipenic rickets, the patient exhibited hypercoagulability, hypokalemia, and secondary amenorrhea. Treatment comprised Vitamin D supplementation (5000 IU) and calcium supplementation. Early diagnosis, guided by history, physical examination, and laboratory and radiological assessments, is essential. The profound impact of rickets on stature and bone structure underscores the urgency of timely diagnosis and appropriate intervention to ensure optimal outcomes for affected individuals.

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Author Biographies

Merylla Filianty Sipayung

Mohammad Hoesin General Hospital, Palembang, Indonesia

Ratna Maila Dewi Anggraini

Mohammad Hoesin General Hospital, Palembang, Indonesia

Alwi Shahab

Mohammad Hoesin General Hospital, Palembang, Indonesia

Yulianto Kusnadi

Mohammad Hoesin General Hospital, Palembang, Indonesia

Mediarty Syahrir

Mohammad Hoesin General Hospital, Palembang, Indonesia

Radiyati Umi Partan

Mohammad Hoesin General Hospital, Palembang, Indonesia

References

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Published

2023-11-09

How to Cite

Sipayung, M. F., Anggraini, R. M. D. ., Shahab, A., Kusnadi, . Y., Syahrir, M., & Partan, R. U. (2023). NAVIGATING THE DIAGNOSTIC CHALLENGES OF CALCIPENIC RICKETS COMPLICATED BY HYPERCOAGULATION, HYPOKALEMIA, AND SECONDARY AMENORRHEA IN A 21-YEAR-OLD FEMALE. Journal of the ASEAN Federation of Endocrine Societies, 38(S3), 47. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/3305

Issue

Vol. 38 No. S3 (2023): AFES Book of Abstracts (Supplement)

Section

Poster Presentation | Bone and Calcium

License

Copyright (c) 2023 Merylla Filianty Sipayung, Ratna Maila Dewi Anggraini, Alwi Shahab, Yulianto Kusnadi, Mediarty Syahrir, Radiyati Umi Partan

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