CASE SERIES OF PRIMARY HYPERPARATHYROIDISM
FROM ASYMPTOMATIC TO FATAL COMPLICATION
Keywords:
primary hyperparathyroidism, parathyroid adenoma, parathyroid carcinoma, hungry bone syndromeAbstract
CASE
Primary hyperparathyroidism is a disorder of the parathyroid glands that causes excessive secretion of parathyroid hormones. The presentation spectrum of PHPT is wide, from asymptomatic to symptomatic. We present four cases of primary hyperparathyroidism (Case 1: 45-year-old female, Case 2: 18-year-old male, Case 3: 36-year-old female, and Case 4: 27-year-old male. All patients were Indonesian), with asymptomatic presentation only in Case I, the rests were symptomatic. Parathyroidectomy was performed in all patients, with the histopathological results of parathyroid adenoma (Cases 1 and 2) and parathyroid carcinoma (Cases 3 and 4). There were hungry bone syndrome complications in both parathyroid carcinoma patients, and one of the patients did not survive due to cardiac arrhythmia. We compare the differences of clinical presentation, biochemical findings, imaging, and the outcomes of all patients, to learn how to treat primary hyperparathyroidism with different presentations.
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Copyright (c) 2023 Muhammad Iman Pratama Putra, Hikmat Permana, Ervita Ritonga, Maya Kusumawati, Nanny Natalia Mulyani Soetedjo
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