EXPERIENCE OF SEVERE HYPERTRIGLYCERIDEMIA MANAGEMENT IN A TERTIARY CENTRE

A CASE SERIES

Authors

  • Shamila Sutharsan
  • Norasyikin Wahab
  • Norlaila Mustafa

Keywords:

diabetes mellitus, severe hypertriglyceridemia, insulin infusion, inpatient

Abstract

CASE
Severe hypertriglyceridemia is defined by levels typically >10 mmol/L. It is often caused by uncontrolled diabetes mellitus, obesity, metabolic syndrome, chronic liver disease, excessive alcohol consumption, and genetic disorders. It is a risk factor for coronary artery disease and acute pancreatitis. We report successful inpatient reduction of severe hypertriglyceridemia in five individuals with intravenous insulin infusion, lipid-lowering oral agents and restriction of dietary carbohydrate and fat intake. More than half of them had underlying diabetes mellitus and triglyceride levels >30 mmol/L on admission. Insulin treatment was given for at least seven days. A lower rate of 0.05 unit/kg per hour insulin infusion and dextrose infusion was initiated for the patient without diabetes. None of them had severe hypoglycemia reported during their stay. They were discharged with triglyceride levels less than 10 mmol/L and subsequently followed up in our centre.

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Author Biographies

Shamila Sutharsan

Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Norasyikin Wahab

Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Norlaila Mustafa

Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

References

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Published

2023-11-09

How to Cite

Sutharsan, S., Wahab, N., & Mustafa, N. . (2023). EXPERIENCE OF SEVERE HYPERTRIGLYCERIDEMIA MANAGEMENT IN A TERTIARY CENTRE: A CASE SERIES. Journal of the ASEAN Federation of Endocrine Societies, 38(S3), 82. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/3435

Issue

Section

Poster Presentation | Miscellaneous

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