FUNCTIONING ADRENOCORTICAL ONCOCYTIC CARCINOMA

A RARE VARIANT

Authors

  • Dineash Kumar Kannesan
  • Teh Roseleen Nadia Roslan
  • Norhayati Yahaya
  • Aniza Hassan
  • Junaidi Awang Isa

Keywords:

ADRENOCORTICAL ONCOCYTIC CARCINOMA, Ki-67, ENSAT Stage 2

Abstract

INTRODUCTION/BACKGROUND
Adrenocortical oncocytic carcinoma (AOC) is a rare histopathological variant of adrenocortical carcinoma (ACC) that is mostly non-functional that are discovered incidentally or present with vague abdominal pain. Functioning AOCs are extremely rare.

CASE
We report the case of a 62-year-old Siamese female who presented with progressive left-sided abdominal pain. Computed tomography demonstrated a huge mass over the left upper retroperitoneal region. Biochemically, the patient had possible autonomous cortisol secretion. Left adrenalectomy was successful with R0 resection, histological examination revealed AOC (based on LinWeiss-Biscelgia score) with Ki-67 of 10% and she was staged as ENSAT Stage 2. She is under periodic imaging surveillance. Nearly 3 years after complete resection, there was no evidence of recurrence or metastasis clinically and radiologically and her cortisol status reverted to normal.

CONCLUSION
In summary, we describe here an extremely rare case of functioning AOC which differs clinically from conventional ACC and showed a more favourable prognosis.

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Author Biographies

Dineash Kumar Kannesan

Endocrine Unit, Hospital Raja Perempuan Zainab II, Kelantan, Malaysia

Teh Roseleen Nadia Roslan

Endocrine Unit, Hospital Raja Perempuan Zainab II, Kelantan, Malaysia

Norhayati Yahaya

Endocrine Unit, Hospital Raja Perempuan Zainab II, Kelantan, Malaysia

Aniza Hassan

Department of Pathology, Hospital Raja Perempuan Zainab II, Kelantan, Malaysia

Junaidi Awang Isa

Department of Pathology, Hospital Raja Perempuan Zainab II, Kelantan, Malaysia

References

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Published

2023-07-06

How to Cite

Kannesan, D. K., Roslan, T. R. N. ., Yahaya, N. ., Hassan, A., & Isa, J. A. . (2023). FUNCTIONING ADRENOCORTICAL ONCOCYTIC CARCINOMA: A RARE VARIANT. Journal of the ASEAN Federation of Endocrine Societies, 38(S2), 19. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/3601

Issue

Vol. 38 No. S2 (2023): MAC13 Book of Abstracts (Special Edition)

Section

Adult | E-Poster

License

Copyright (c) 2023 Dineash Kumar Kannesan, Teh Roseleen Nadia Roslan, Norhayati Yahaya, Aniza Hassan, Junaidi Awang Isa

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