Indonesian Clinical Practice Guidelines for Diabetes in Pregnancy

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Dyah Purnamasari
Sarwono Waspadji
John MF Adam
Ahmad Rudijanto
Dicky Tahapary


Diabetes Mellitus (DM) in pregnancy has serious impact on both mother and baby if not optimally managed. The Indonesian Task Force on Reproductive Diseases determined that diabetes in pregnancy represents a priority area in need of updated evidence-based practice guidelines. The aim of the guidelines is to provide the best evidence-based recommendations for diagnostic evaluation and management of diabetes in pregnancy. The following article summarizes the guidelines.


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Purnamasari, D., Waspadji, S., Adam, J. M., Rudijanto, A., & Tahapary, D. (2014). Indonesian Clinical Practice Guidelines for Diabetes in Pregnancy. Journal of the ASEAN Federation of Endocrine Societies, 28(1), 9. Retrieved from
Feature Articles


Konsensus Diagnosis dan Penatalaksanaan Diabetes Melitus Gestasional. Perkumpulan Endokrinologi Indonesia, 1997.

Waspadji S. Diabetes mellitus pada kehamilan. Dalam: Markum, HMS. Sudoyo AW, Effendy S, Setiati S, Gani RA, Alwi I. Naskah lengkap Pertemuan Ilmiah Tahunan Ilmu Penyakit Dalam 1997. Bagian Ilmu Penyakit Dalam FKUI/ RSUPN dr. Cipto Mangunkusumo, Jakarta, 1997.

Ben-Haroush A, Yogev Y, Hod M. Epidemiology of gestational diabetes melitus and its association with type 2 diabetes. Diabet Med. 2004; 21:103-13.

Retnakaran R, Hanley AJG, Connely PW, Sermer M, Zinman B. Ethnicity modifies the effect of obesity on insulin resistance in pregnancy: A comparison of Asian, South Asian and Caucasian women. J Clin Endocrinol Metab. 2006; 91: 93-7.

Hod M, Yogey Y. Goals of metabolic management of gestational diabetes. Diabetes Care. 2007; 30(suppl2): S180-7.

Metzger BE, Buchanan TA, Organizing Committee. Summary and recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care. 2007; 30(suppl2): 251S-60S.

Konsensus diagnosis dan penatalaksanaan diabetes melitus di Indonesia. Perkumpulan Endokrinologi Indonesia, Jakarta 2006.

Waspadji S, Napitupulu B, Hasanuddin F, Supartondo. Kadar glukosa darah puasa, sesudah makan dan kadar gliko Hb pada wanita hamil non diabetes melitus. Dalam: Tjokroprawiro A, Sukahatya M, Suhadi B, Sutjahjo A, Tandra H, Buku naskah lengkap. Kongres nasional II Perkumpulan Endokrinologi Indonesia. Surabaya 1989.

Kjos SL, Schaefer-Graf UM, Modified therapy for gestational diabetes using high risk and low risk fetal abdominal circumference growth to select strict versus relaxed maternal glycemic target. Diabetes Care. 2007; 30 (suppl 2): S200-5.

Kjos SL, Buchanan TA. Gestational Diabetes Mellitus. N Engl J Med. 1999; 341: 1749-56.

Ben-Haroush A, Yogev Y, Hod M. Epidemiology of gestational diabetes melitus and its association with type 2 diabetes. Diabet Med. 2004; 21:103-13.

Jovanovic L. Point: Oral hypoglycaemic agents should not be used to treat diabetic pregnant women. Editorials. Diabetes Care. 2007; 30: 2976-9.

Committee on Nutritional Status During Pregnancy and Lactation, Institute of Medicine. Nutrition During Pregnancy: Part I: Weight Gain, Part II: Nutrient Supplements. National Academy Press, Washington, DC, 1990.

Bloomgarden ZT. Gestational Diabetes Mellitus and Obesity. Diabetes Care. 2010; 33(5). E60-e65.

Chamim. Penatalaksanaan diabetes dalam kehamilan. Tesis. Bagian Obstetri & Ginekologi FKUI/ RSCM Jakarta 1995.

Reader DM. Medical nutrition therapy and lifestyle interventions. Diabetes Care. 2007; 30: S188-S193.

Snyder J, Gray-Donald K. Koski KG. Predictors of infant birthweight in gestational diabetes. Am J Clin Nutr. 1994; 59 : 1409-1414.

Harris GD, White RS. Diabetes management and exercise in pregnant patients with diabetes. Clinical Diabetes. 2005; 23(4) :165-8.

Balaji V, Madhuri BS, Ashalatha S, Sheela S, Suresh S, Seshiah V. A1c in gestational diabetes melitus in Asian Indian women. Diabetes Care. 2007; 30: 1865-7.

Kahn BF, Davies JK, Lynch AM, Reynolds RM, Barbour LA, Predictors of glyburide failure in the treatment of gestational diabetes. Obstet Gynecol. 2006; 107: 1303-9.

Langer O, Conway DL, Berkus MD, Xenakis EM, Gonzales O. A comparison of glyburide and insulin in women with gestational diabetes melitus. N Engl J Med. 2000; 343: 1134-8.

Moore TR. Glyburide for the treatment of gestational diabetes. A critical appraisal. Diabetes Care. 2007; 30 (suppl2): s209-13.

Ho FL, Liew CH, Cunanan EC, Lee KO, Oral hypoglycaemic agents for diabetes in pregnancy. An appraisal of the current evidence for oral anti-diabetic drug use in pregnancy. Ann Acad Med Singapore. 2007; 36; 672-8.

Rowan JA, Hague WM, Gao W, Battin MR, Moore P. Metformin versus insulin for the treatment of gestational diabetes. N Engl J Med. 2008; 358:2003-15.

Wendyansyah. Perbandingan pengendalian gula darah dan luaran kehamilan pasien diabetes mellitus gestasional pada pemberian metformin dengan metode standar. Tesis. Program Studi Obstetri dan Ginekologi Program Pendidikan Dokter Spesialis I. FKUI RSCM Jakarta 2005.

Jovanovic L, Pettitt DJ. Treatment with insulin and its analogs in pregnancies complicated by diabetes. Diabetes Care. 2007; 30(suppl2) S220-4.

Pantalone KM, Faiman C, Olansky L. Insulin glargine use during pregnancy. Endocrine Practice. 2011;17 (No.3).

deValk HW, Visser GHA. Insulin during pregnancy, labour, and delivery. Best Practice & Research Clinical Obstetrics and Gynaecology. 2011; 25 :65-76.

Negrato CA, Rafacho A, Negrato G, Teixeira MF, Araujo CAR, et al. Glargine vs NPH insulin therapy in pregnancies complicated by diabetes: An observational cohort study. Diabetes Research and Clinical Practice. 2010; 89: 46-51.

Leperq J, Lin J, Hall GC, Wang E, Dai MP, et al. Meta-Analysis of maternal and neonatal outcomes associated with the use of insulin glargine versus NPH insulin during pregnancy. Obstetrics and Gynecology International. doi:10.1155/2012/649070.

Cianni GD, Volpe L, Ghio A, Lencioni C, Cuccuru I, Benzi L, et al. Maternal metabolic control and perinatal outcome in women with gestational diabetes melitus treated with lispro or aspart insulin. Comparison with regular insulin. Letters. Diabetes Care. 2007; 30: e11.

Pettitt DJ, Ospina P, Howard C, Zisser H, Jovanovic L. Efficacy, safety and lack of immunogenicity of insulin aspart compared with regular human insulin for women with gestational diabetes mellitus. Diabet Med. 2007; 24: 1129-35.

Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS, et al. Effect of treatment gestational diabetes mellitus on pregnancy outcome. N Engl J Med. 2005; 352; 2477-86.

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