Communicating Hydrocephalus in a Case of Long-Term Primary Hyperparathyroidism



cinacalcet, hydrocephalus, hypercalcemia, hyperparathyroidism, primary, osteitis fibrosis cystica


We present the rare case of a 47-year-old woman with protracted primary hyperparathyroidism complicated by communicating hydrocephalus and cerebellar tonsillar herniation secondary to calvarial thickening. The parathyroid glands remained elusive, despite the use of advanced preoperative imaging modalities and three neck explorations. The serum calcium was optimally controlled with cinacalcet and alfacalcidol. Awareness of this rare complication is essential for early diagnosis and prompt intervention to prevent fatal posterior brain herniation.


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Author Biographies

Cheow Peng Ooi, 1. Universiti Putra Malaysia 2. Pusat Perubatan Universiti Kebangsaan Malaysia

Lecturer in Medicine

Norlaila Mustafa, Pusat Perubatan Universiti Kebangsaan Malaysia

Associate Professor,

Senior Consultant Endocrinologist


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How to Cite

Ooi, C. P., Mustafa, N., & Kew, T. Y. (2018). Communicating Hydrocephalus in a Case of Long-Term Primary Hyperparathyroidism. Journal of the ASEAN Federation of Endocrine Societies, 33(1), 49. Retrieved from



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