Prevalence of Sexual Dysfunction and its Associated Factors among Women with Diabetes Mellitus Type 2 at Makati Medical Center Outpatient Department
Keywords:
sexual dysfunction, type 2 diabetes mellitus, premenopause, diabetic neuropathies, diabetic retinopathy, diabetic nephropathiesAbstract
*Visual Abstract prepared by Dr. Francis Xavier Mislang
Objective. This study aims to determine the prevalence of sexual dysfunction among premenopausal Filipino women with type 2 diabetes mellitus at the outpatient department of a tertiary hospital through the use of the Female Sexual Function Index (FSFI) and identify factors that could be associated with sexual dysfunction.
Methodology. Seventy-five women with type 2 diabetes mellitus, aged 38 to 49 years old, received the FSFI questionnaire. Their age, history of hypertension, smoking habit, alcohol intake, body mass index, waist circumference, fasting blood sugar, HbA1c, creatinine, lipid profile, albuminuria or proteinuria, presence of microvascular complications such as diabetic retinopathy, neuropathy and nephropathy and their association with sexual dysfunction was determined.
Results. Seventy-two percent of the participants have sexual dysfunction scoring lowest in the lubrication, orgasm and pain domains. Age (p=0.016), a high body mass index (p=0.001), a fasting blood sugar above 100 mg/dl (p=0.006) and the presence of microvascular complications of diabetes mellitus namely, retinopathy (p=0.046) nephropathy (p=0.004) and neuropathy (p=0.001) were associated with sexual dysfunction.
Conclusion. The prevalence of sexual dysfunction is high among premenopausal Filipino women with type 2 diabetes mellitus, and is associated with age, a high body mass index, an uncontrolled fasting blood sugar and the presence of microvascular complications of diabetes mellitus.
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References
American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed. USA: Washington, DC, 2013. https://doi.org/10.1176/appi.books.9780890425596.
Vafaeimanesh J, Raei M, Hosseizaddeh F, Farham M. Evaluation of sexual dysfunction in women with type 2 diabetes. Indian J Endocrinol Metab. 2014;18(2):175-9. PMID: 24741512. PMCID: PMC3987266. https://doi.org/10.4103/2230-8210.129107.
Rosen RC, Brown C, Heiman J, et al. The Female Sexual Function Index (FSFI): A multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26(2):191-208. PMID: 10782451. https://doi.org/10.1080/009262300278597.
Fatemi SS, Taghavi SM. Evaluation of sexual function in women with type 2 diabetes mellitus. Diab Vasc Dis Res. 2009;6(1):38-9. PMID: 19156627. https://doi.org/10.3132/dvdr.2009.07.
Binmoammar TA, Hassounah D, Alsaad S, Rawaf S, Majeed A. The impact of poor glycemic control on the prevalence of erectile dysfunction in men with type 2 diabetes mellitus: A systemic review. JRSM Open. 2016;7(3):2054270415622602. PMID: 26981254.PMCID: PMC4776250. https://doi.org/10.1177/2054270415622602.
Cortelazzi D, Marconi A, Guazzi M. Sexual dysfunction in pre-menopausal diabetic women: Clinical, metabolic, psychological, cardiovascular, and neurophysiologic correlates. Acta Diabetol. 2013;50(6):911-7. PMID: 23677545. https://doi.org/10.1007/s00592-013-0482-x.
Bargiota A, Dimitropoulos K, Tzortzis V, Koukoulis GN. Sexual dysfunction in diabetic women. Hormones (Athens). 2011;10(3):196-206. PMIDL 22001130.
Ogbera AO, Chinenye S, Akinlade A, Eregie A, Awobusuyi J. Frequency and correlates of sexual dysfunction in women with diabetes mellitus. J Sex Med. 2009;6(12):3401-6. PMID: 19627467. https://doi.org/10.1111/j.1743-6109.2009.01396.x.
Pontiroli AE, Cortellazi D, Morabito A, Female sexual dysfunction and Diabetes: A systemic review and meta-analysis. J Sex Med. 2013;10(4):1044-51. PMID: 23347454. https://doi.org/10.1111/jsm.12065.
Unite for Diabetes Philippines 2011: Philippine practice guidelines for the diagnosis and management of diabetes. https://www.diabetesphil.org/html/files/clinical_practice_guidelines_draft.pdf.
Menopause terminology http://www.imsociety.org/menopause_terminology.php. Accessed July 25, 2018.
Esposito K, Ciotola M, Marfella R, Di Tommaso D, Cobellis L, Giugliano D. Sexual dysfunction in women with metabolic syndrome. Diabetes Care. 2005;28(3):756. PMID: 15735227.
Huang PL. A comprehensive definition for metabolic syndrome. Dis Model Mech. 2009;2(5-6): 231-7. PMID: 19407331. PMCID: PMC2675814. https://doi.org/10.1242/dmm.001180.
American Diabetes Association. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes - 2018. Diabetes Care. 2018;41(Suppl 1):S12-27. PMID: 29222373. https://doi.org/10.2337/dc18-S002.
Boulton A, Armstrong D, Albert S, et al. Comprehensive foot examination and risk assessment: A report of the task force of the foot care interest group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists. Phys Ther. 2008;88(11):1436-43. PMID: 19137633.
Wiegel M, Meston C, Rosen R. The female sexual function Index (FSFI) cross-validation and development of clinical cut-off scores. J Sex Marital Ther. 2005;31(1):1-20. PMID: 15841702. https://doi.org/10.1080/00926230590475206.
Rillon-Tabil N, Malong CLP, Vicere JJB, Gomez MHS. Translation and validity of the Female Sexual Function Index Filipino Version (FSFI-Fil). Philipp J Int Med. 2013; 51(4):1-11.
Esposito K, Maiorino MI, Bellastella G, Giugliano F, Romano M, Giugliano D. Determinants of female sexual dysfunction in type 2 diabetes. Int J Impot Res. 2010;22(3):179-84. PMID: 20376056. https://doi.org/10.1038/ijir.2010.6.
Lewis RW. Epidemiology of sexual dysfunction in Asia compared to the rest of the world. Asian J Androl. 2011;13(1):152-8. PMID: 21076440. PMCID: PMC3739382. https://doi.org/10.1038/aja.2010.108.
Celik S, Golbasi Z, Kelleci M, Satman I. Sexual dysfunction and sexual quality of life in women with diabetes: The study based on a diabetic center. Sex Disabil. 2015;33(2):233-41. https://doi.org/10.1007/s11195-014-9383-3.
Shi YF, Shao XY, Lou QQ, Chen YJ, Zhou HJ, Zou JY. Study on female sexual dysfunction in type 2 diabetic Chinese women. Biomed Environ Sci. 2012;25(5):557-61. PMID: 23122313. https://doi.org/10.3967/0895-3988.2012.05.009.
Doruk H, Akbay E, Cayan S, Akbay E, Bozlu M, Acar D. Effect of diabetes mellitus on female sexual function and risk factors. Arch Androl. 2005;51(1):1-6. PMID: 15764412. https://doi.org/10.1080/014850190512798.
Elyasi F, Kashi Z, Tasfieh B, Bahar A, Khademloo M. Sexual dysfunction in women with type 2 diabetes mellitus. Iran J Med Sci. 2015;40(3):206-13. PMID: 25999619. PMCID: PMC443088.
Azadzoi KM, Siroky MB. Neurologic factors in female sexual function and dysfunction. Korean J Urol. 2010;51(7):443-9. PMID: 20664775. PMCID: PMC2907491. https://doi.org/10.4111/kju.2010.51.7.443.
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