Thymic Hyperplasia-Associated Myasthenia Gravis in the Setting of Coexisting Graves’ Disease
DOI:
https://doi.org/10.15605/jafes.040.02.04Keywords:
thymic hyperplasia, Myasthenia gravis, Graves' diseaseAbstract
Thymic hyperplasia secondary to Graves’ disease (GD) is a well-recognized entity.¹ Still, other causes of thymic hyperplasia in the presence of euthyroidism, especially the occurrence of massive thymic hyperplasia, should be investigated.² The clinical features of myasthenia gravis (MG) and thyroid eye disease (TED) may be similar, while thymic hyperplasia may occur in both conditions. Herein, we report an interesting case of the coexistence of severe TED and MG.
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1. Popoveniuc G, Sharma M, Devdhar M, et al. Graves’ disease and thymic hyperplasia: The relationship of thymic volume to thyroid function. Thyroid. 2010;20:1015–8. https://pubmed.ncbi.nlm.nih.gov/20718680 https://doi.org/10.1089/thy.2009.0383
2. Haider U, Richards P, Gianoukakis AG. Thymic hyperplasia associated with Graves’ disease: Pathophysiology and proposed management algorithm. Thyroid. 2017;27(8):994–1000. https://pubmed.ncbi.nlm.nih.gov/28578595 https://doi.org/10.1089/thy.2017.0086
3. Lopomo A, Berrih-Aknin S. Autoimmune thyroiditis and myasthenia gravis. Front Endocrinol (Lausanne). 2017;8:169. https://pubmed.ncbi.nlm.nih.gov/28751878 https://pmc.ncbi.nlm.nih.gov/articles/PMC5508005 https://doi.org/10.3389/fendo.2017.00169
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