Sarcopenia Can Be Physiological or Pathological, Primary or Secondary

Authors

  • Josef Finsterer Neurology and Neurophysiology Center, Vienna, Austria

DOI:

https://doi.org/10.15605/jafes.041.03.5127

Keywords:

sarcopenia, muscle wasting, cardiovascular disease, aging

Abstract

In response to the article, “Interrelationship of Sarcopenia and Cardiovascular Diseases:
A Review of Potential Mechanisms and Management,” by Rivera, et al., published in JAFES Vol. 39 No. 1.

We read with interest the review article by Rivera et al., on the relationship between sarcopenia and cardiovascular diseases such as atherosclerosis, hypertension, coronary heart disease, and heart failure.1 Cardiovascular diseases have been found to trigger sarcopenia through processes such as inflammation, oxidative stress, endothelial dysfunction, neuronal and hormonal changes, malnutrition, and reduced physical activity.1 It was concluded that cardiovascular drugs, hormone replacement, changes in diet and nutritional intake, and physical activity can attenuate sarcopenia.1 The study is noteworthy, but some points warrant discussion.

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References

1. Rivera FB, Escolano BT, Nifas FM, et al. Interrelationship of sarcopenia and cardiovascular diseases: A review of potential mechanisms and management. J ASEAN Fed Endocr Soc. 2024;39(1):69-78. https://pubmed.ncbi.nlm.nih.gov/38863922 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11163321 https://doi.org/10.15605/jafes.039.01.03

2. Powers SK, Lynch GS, Murphy KT, Reid MB, Zijdewind I. Disease-induced skeletal muscle atrophy and fatigue. Med Sci Sports Exerc. 2016;48(11):2307-19. https://pubmed.ncbi.nlm.nih.gov/27128663 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069191 https://doi.org/10.1249/MSS.0000000000000975

3. Kemmler W, Bebenek M, Engelke K, von Stengel S. Impact of whole-body electromyostimulation on body composition in elderly women at risk for sarcopenia: The training and electrostimulation trial (TEST-III). Age (Dordr). 2014;36(1):395-406. https://pubmed.ncbi.nlm.nih.gov/23949160 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889893 https://doi.org/10.1007/s11357-013-9575-2

4. Campins L, Camps M, Riera A, Pleguezuelos E, Yebenes JC, Serra-Prat M. Oral drugs related with muscle wasting and sarcopenia. A review. Pharmacology. 2017;99(1-2):1-8. https://pubmed.ncbi.nlm.nih.gov/27578190 https://doi.org/10.1159/000448247

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Published

2026-10-11

How to Cite

Finsterer, J. (2026). Sarcopenia Can Be Physiological or Pathological, Primary or Secondary. Journal of the ASEAN Federation of Endocrine Societies. https://doi.org/10.15605/jafes.041.03.5127

Issue

Section

Letters to the Editor