THE CORRELATION BETWEEN HYPERTENSION IN COMBINATION WITH PROTEINURIA AND HEART FAILURE EVENTS IN T2DM PATIENTS (BUITENZORG STUDY PRELIMINARY REPORT)

Abstract

OBJECTIVES
The contribution of proteinuria in combination with hypertension to heart failure events has been shown in previous study, but little information is available in developing countries, particularly in a low-resource setting. This pilot study aimed to evaluate the risk of a history of hypertension and proteinuria as a potential early recognition of heart failure in adults with type 2 diabetes mellitus.

METHODOLOGY
This study was a multicentre and observational study with cross-sectional design approach. A total of 153 T2DM were enrolled from three internal medicine clinics in Bogor, West Java, between January 2018 and March 2018. They had been controlled and treated with their routine glucose lowering drugs. Echocardiography was used to evaluate their heart function in a real-world setting. More data were collected from the integrated retrospective data reserve in electronic or written medical records of each clinic.

RESULTS
Correlative analysis between hypertension and heart failure events was analysed using Spearman test. The stratum analysis between hypertension, proteinuria and heart failure events was also conducted using Chi-Square. All the statistical analysis used the significance p value of <0.05.

CONCLUSION
There was significant correlation between hypertension in combination with proteinuria with heart failure events in type 2 diabetic patients.