Letter to the Editor on the article, 'Perioperative Complications Associated with Routine Preoperative Glucocorticoid Use Among Patients Undergoing Pituitary Surgery with Normal Preoperative HPA Axis: A Retrospective Cohort Study'
by Magnaye and Paz-Pacheco, published in JAFES Vol 40. No. 1
DOI:
https://doi.org/10.15605/jafes.041.01.6257Keywords:
hypothalamic-pituitary-adrenal axis, glucocorticoids, perioperative complicationsAbstract
This letter addresses the recent study by Magnaye et al., which investigated the impact of routine preoperative glucocorticoid administration in patients with a normal hypothalamic-pituitary-adrenal (HPA) axis undergoing pituitary surgery. The authors are commended for their valuable contribution to understanding steroid-related perioperative outcomes. However, we highlight the need for further clarification regarding the wide range of steroid regimens reported and the absence of detailed information on timing, indications, and factors influencing steroid administration. Additionally, differentiating between transient and permanent postoperative diabetes insipidus could provide deeper insight into the observed higher incidence among steroid-treated patients. Addressing these aspects, along with establishing standardized steroid protocols, could enhance the specificity and clinical applicability of the study’s findings.
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Magnaye FM, Paz-Pacheco E. Perioperative complications associated with routine preoperative glucocorticoid use among patients undergoing pituitary surgery with normal preoperative HPA axis: A retrospective cohort study. ASEAN Fed Endocr Soc. 2025;40(1):89-96. https://pubmed.ncbi.nlm.nih.gov/40416483 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097979 https://doi.org/10.15605/jafes.040.01.06
Chen Cardenas SM, Santhanam P, Morris-Wiseman L, et al. Perioperative evaluation and management of patients on glucocorticoids. J Endocr Soc. 2022;7(2):bvac185. https://pubmed.ncbi.nlm.nih.gov/36545644 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760550 https://doi.org/10.1210/jendso/bvac185
Almalki MH, Ahmad MM, Brema I, et al. Management of diabetes insipidus following surgery for pituitary and suprasellar tumours. Sultan Qaboos Univ Med J. 2021;21(3):354-64. https://pubmed.ncbi.nlm.nih.gov/34522399 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407907 https://doi.org/10.18295/squmj.4.2021.010
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Copyright (c) 2026 Eisha Fatimah, Sarosh Usman, Muhammad Aqib Farooq Khan

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