A Case of Appendiceal Goblet Cell Carcinoid Tumor: Getting it right under the Microscope

Waye Hann Kang; Norasyikin Abdul Wahab; Nor Azmi Kamaruddin

doi:10.15605/jafes.035.01.16

Authors

Waye Hann Kang University Tunku Abdul Rahman http://orcid.org/0000-0003-3209-7196
Norasyikin Abdul Wahab Pusat Perubatan Universiti Kebangsaan Malaysia https://orcid.org/0000-0002-1168-217X
Nor Azmi Kamaruddin Pusat Perubatan Universiti Kebangsaan Malaysia https://orcid.org/0000-0001-7600-3273

DOI:

https://doi.org/10.15605/jafes.035.01.16

Keywords:

goblet cell carcinoid, mized neuroendocrine-non-endocrine neoplasm, MINEN, histopathology

Abstract

Goblet cell carcinoid (GCC) is a rare neoplasm of the vermiform appendix and can be mistaken as a typical
neuroendocrine tumour (TNET). The natural history of this disease is more aggressive compared to TNETs and
requires a more aggressive approach. We report a case of a 37-year-old male who was initially diagnosed with TNET, but subsequently revised as Tang’s A GCC. He underwent appendectomy and right hemicolectomy. Aside from a persistently elevated carcinoembyrogenic antigen (CEA) result, his ¹⁸F-fluorodeoxyglucose (FDG) PET/CT and a 68-Gallium DOTATATE PET/CT scan showed no FDG or DOTATATE avid lesions.

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Author Biographies

Waye Hann Kang, University Tunku Abdul Rahman

Lecturer

Department of Medicine, Faculty of Medicine and Health Sciences

Norasyikin Abdul Wahab, Pusat Perubatan Universiti Kebangsaan Malaysia

Department of Medicine

Nor Azmi Kamaruddin, Pusat Perubatan Universiti Kebangsaan Malaysia

Department of Medicine

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