Ectopic ACTH Syndrome – Experience with Etomidate


  • Chin Voon Tong Department of Medicine, Malacca Hospital
  • Zanariah Hussein Endocrine Unit, Department of Medicine, Putrajaya Hospital


etomidate, ectopic ACTH syndrome, Cushing’s syndrome


For ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS), when surgery is not feasible, or in cases of severe biochemical disturbances, immunosuppression or mental instability, medical therapy with agents such as etomidate is indicated. We present our experience in using etomidate for a 41-year old female with EAS secondary to a malignant mediastinal paraganglioma. We were able to demonstrate that etomidate can be used effectively to control severe hypercortisolism in a lower dose than previously described.


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How to Cite

Tong, C. V., & Hussein, Z. (2017). Ectopic ACTH Syndrome – Experience with Etomidate. Journal of the ASEAN Federation of Endocrine Societies, 32(1), 54. Retrieved from



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