Weathering the Crisis: A Case of Thyroid Crisis with Propranolol-Induced Circulatory Collapse Successfully Treated with Therapeutic Plasma Exchange

Keywords: thyroid crisis, circulatory collapse, cardiomyopathy, propranolol, therapeutic plasma exchange

Abstract

Thyroid crisis is a life-threatening form of thyrotoxicosis characterized by multi-system dysfunction. Therapeutic plasma exchange has been reported to be effective in removing excessive circulating thyroid hormones. We present a 46-year-old female with recently diagnosed Graves’ disease associated with thyrotoxic cardiomyopathy admitted for thyroid crisis complicated by propranolol-induced circulatory collapse, acute kidney injury and ischemic hepatitis. The tachyarrhythmia was refractory to conventional therapy. Initiation of TPE resulted in rapid clinical and biochemical stabilization.

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Author Biographies

Jean Mun Cheah, Selayang Hospital, Ministry of Health
Endocrine Unit, Department of Medicine
Danish Ng, Selayang Hospital, Ministry of Health

Consultant Endocrinologist

Endocrine Unit, Department of Medicine

Ming Yong Low, Selayang Hospital, Ministry of Health
Department of Nephrology
Siew Hui Foo, Selayang Hospital, Ministry of Health

Consultant Endocrinologist

Endocrine Unit, Department of Medicine

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Published
2019-11-26
How to Cite
Cheah, J. M., Ng, D., Low, M. Y., & Foo, S. H. (2019). Weathering the Crisis: A Case of Thyroid Crisis with Propranolol-Induced Circulatory Collapse Successfully Treated with Therapeutic Plasma Exchange. Journal of the ASEAN Federation of Endocrine Societies, 34(2), 206-209. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/559
Section
Case Reports