A Trial of Oral Glucocorticoids in the Resolution of Recurrent Granulomatous Hypophysitis
A Case Report
DOI:
https://doi.org/10.15605/jafes.034.02.13Keywords:
granulomatous hypophysitis, autoimmune hypophysitis, glucocorticoidsAbstract
Granulomatous hypophysitis is an extremely rare condition, with no established definitive treatment. An elderly Asian woman was diagnosed to have recurrent granulomatous hypophysitis 5 years after transsphenoidal surgery. No other intervention was done post-operatively. Since another surgery was not advisable due to the high probability of recurrence, she was started on a trial of oral glucocorticoids. After 3 months of steroid therapy, complete resolution of symptoms and sellar mass were achieved.
Downloads
References
Prete A, Salvatori R. Hypophysitis. 2018. In: Feingold KR, Anawalt B, Boyce A, et al., eds. Endotext [Internet]. South Dartmouth, MA:MDText.com, Inc., 2000-. https://www.ncbi.nlm.nih.gov/books/NBK519842/.
Park HJ, Park SH, Kim JH, Kim YH. Idiopathic Granulomatous Hypophysitis with Rapid Onset: A Case Report. Brain Tumor Res Treat. 2019 Apr;7(1):57-61.https://doi.org/10.14791/btrt.2019.7.e22.
Hunn BHM, Martin WG, Simpson S, Mclean CA. Idiopathic granulomatous hypophysitis: a systematic review of 82 cases in the literature. Pituitary. 2014;17(4):357-65. https://doi.org/10.1007/s11102-013-0510-4.
Elgamal ME, Mohamed RMH, Fiad T, Elgamal EA. Granulomatous hypophysitis: rare disease with challenging diagnosis. Clin Case Rep. 2017;5(7):1147-51. https://www.ncbi.nlm.nih.gov/pubmed/28680614. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494403. https://doi.org/ 10.1002/ccr3.1007.
Shi J, Zhang J, Wu Q, Chen G, Zhang H, Bo W. Granulomatous hypophysitis: two case reports and literature review. J Zhejiang Univ Sci B. 2009;10(7):552-8. https://www.ncbi.nlm.nih.gov/pubmed/19585674. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704974. https://doi.org/10.1631/jzus.B0820355.
Published
How to Cite
Issue
Section
License
Journal of the ASEAN Federation of Endocrine Societies is licensed under a Creative Commons Attribution-NonCommercial 4.0 International. (full license at this link: http://creativecommons.org/licenses/by-nc/3.0/legalcode).
To obtain permission to translate/reproduce or download articles or use images FOR COMMERCIAL REUSE/BUSINESS PURPOSES from the Journal of the ASEAN Federation of Endocrine Societies, kindly fill in the Permission Request for Use of Copyrighted Material and return as PDF file to jafes@asia.com or jafes.editor@gmail.com.
A written agreement shall be emailed to the requester should permission be granted.