A Trial of Oral Glucocorticoids in the Resolution of Recurrent Granulomatous Hypophysitis
A Case Report
DOI:
https://doi.org/10.15605/jafes.034.02.13Keywords:
granulomatous hypophysitis, autoimmune hypophysitis, glucocorticoidsAbstract
Granulomatous hypophysitis is an extremely rare condition, with no established definitive treatment. An elderly Asian woman was diagnosed to have recurrent granulomatous hypophysitis 5 years after transsphenoidal surgery. No other intervention was done post-operatively. Since another surgery was not advisable due to the high probability of recurrence, she was started on a trial of oral glucocorticoids. After 3 months of steroid therapy, complete resolution of symptoms and sellar mass were achieved.
Downloads
References
Prete A, Salvatori R. Hypophysitis. 2018. In: Feingold KR, Anawalt B, Boyce A, et al., eds. Endotext [Internet]. South Dartmouth, MA:MDText.com, Inc., 2000-. https://www.ncbi.nlm.nih.gov/books/NBK519842/.
Park HJ, Park SH, Kim JH, Kim YH. Idiopathic Granulomatous Hypophysitis with Rapid Onset: A Case Report. Brain Tumor Res Treat. 2019 Apr;7(1):57-61.https://doi.org/10.14791/btrt.2019.7.e22.
Hunn BHM, Martin WG, Simpson S, Mclean CA. Idiopathic granulomatous hypophysitis: a systematic review of 82 cases in the literature. Pituitary. 2014;17(4):357-65. https://doi.org/10.1007/s11102-013-0510-4.
Elgamal ME, Mohamed RMH, Fiad T, Elgamal EA. Granulomatous hypophysitis: rare disease with challenging diagnosis. Clin Case Rep. 2017;5(7):1147-51. https://www.ncbi.nlm.nih.gov/pubmed/28680614. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494403. https://doi.org/ 10.1002/ccr3.1007.
Shi J, Zhang J, Wu Q, Chen G, Zhang H, Bo W. Granulomatous hypophysitis: two case reports and literature review. J Zhejiang Univ Sci B. 2009;10(7):552-8. https://www.ncbi.nlm.nih.gov/pubmed/19585674. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704974. https://doi.org/10.1631/jzus.B0820355.
Published
How to Cite
Issue
Section
License
The full license text is available at: http://creativecommons.org/licenses/by-nc/3.0/legalcode.
To request permission to translate, reproduce, download, or use articles or images for commercial reuse or business purposes from the Journal of the ASEAN Federation of Endocrine Societies (JAFES), kindly complete the Permission Request for Use of Copyrighted Material Form and email jafes@asia.com or jafes.editor@gmail.com.
A written agreement will be issued to the requester once permission has been granted.




