Simultaneous Occurrence of Papillary Carcinoma and Medullary Carcinoma

Authors

DOI:

https://doi.org/10.15605/jafes.034.02.16

Keywords:

thyroid cancer, papillary thyroid cancer, medullary thyroid cancer

Abstract

The cell origin, histopathologic features, and prognosis of medullary and papillary thyroid carcinoma are different and to have them occur simultaneously in a single patient is a rare occurrence.

This is a case of a 38-year-old female who presented with an enlarging anterior neck mass whose fine needle aspiration biopsy could not rule out a papillary lesion. Thus, she was advised to undergo total thyroidectomy, and her final histopath showed a simultaneous medullary and papillary thyroid carcinoma. Her initial serum calcitonin was elevated at 252 pg/ ml, and it remained persistently elevated over the course of 7 months. A repeat ultrasound revealed solid nodules with coarse calcifications and enlarged lymph nodes at both submandibular regions. This warranted a repeat surgery with neck dissection with the finding of eight lymph nodes positive for metastatic carcinoma. On follow up after her second surgery, the calcitonin decreased to 42.70 pg/ml.

Knowledge of this simultaneous occurrence of medullary thyroid carcinoma and papillary cancer is important for its prognostic implications and therapeutic plan.

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Author Biographies

Lyza Camille Gadong, Makati Medical Center

Endocrine Fellow in Training

Section of Endocrinology, Diabetes and Metabolism

Department of Internal Medicine

 

Thelma Crisostomo, Makati Medical Center

Section of Endocrinology, Diabetes and Metabolism

Department of Internal Medicine

References

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Published

2019-11-26

How to Cite

Gadong, L. C., & Crisostomo, T. (2019). Simultaneous Occurrence of Papillary Carcinoma and Medullary Carcinoma. Journal of the ASEAN Federation of Endocrine Societies, 34(2), 226–228. https://doi.org/10.15605/jafes.034.02.16

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Section

Case Reports