Metastatic Adenocarcinoma Arising from Fibrocalcific Pancreatic Diabetes

Authors

  • Deep Dutta Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India
  • Manoj Kumar Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India
  • Rajesh Jain Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India
  • Anubhav Thukral Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India
  • Dibakar Biswas Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India
  • Sujoy Ghosh Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India
  • Satinath Mukhopadhyay Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India
  • Subhankar Chowdhury Department of Endocrinology and Metabolism, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India

Abstract

Fibrocalcific pancreatic diabetes (FCPD) is a rare form of ketosis-resistant diabetes in the young (15 to 40 years old) of unknown etiology. It has been observed in tropical and subtropical countries with highest incidence in south India, and is believed to have some association with tropical chronic pancreatitis, malnutrition, toxin exposure (e.g., cassava) and SPINK1 mutation. It is associated with a hundredfold increased risk of pancreatic cancer compared to the general population

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References

Bhatia E, Choudhuri G, Sikora SS et al. Tropical calcific pancreatitis: Strong association with SPINK1 trypsin inhibitor mutation. Gastroenterology 2002;123(4):1020-5.

Braganza JM, Sherry J, Indira P et al. Xenobiotics and tropical chronic pancreatitis. Int J Pancreatology 1990:222–45.

Chari ST, Mohan V, Pitchumoni CS et al. Risk of pancreatic carcinoma in tropical calcific pancreatitis: An epidemiologic study. Pancreas 1994;9(1):62-6.

Published

2014-05-25

How to Cite

Dutta, D., Kumar, M., Jain, R., Thukral, A., Biswas, D., Ghosh, S., … Chowdhury, S. (2014). Metastatic Adenocarcinoma Arising from Fibrocalcific Pancreatic Diabetes. Journal of the ASEAN Federation of Endocrine Societies, 28(2), 165. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/72

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